Tarzana (pronounced /tɑrˈzænə/) is a district in the San Fernando Valley region of the city of Los Angeles, California, United States.

Tarzana, a district of Los Angeles, is surrounded by Reseda to the north, Woodland Hills to the west, Encino to the east, and the Santa Monica Mountains (also a part of Los Angeles) to the south. Major roads in Tarzana include Reseda Boulevard, Tampa Avenue, Wilbur Avenue, Burbank Boulevard, and Ventura Boulevard, the commercial backbone of the southern San Fernando Valley,

Most of Tarzana’s inhabitants live in the foothills of the Santa Monica Mountains south of Ventura Boulevard. North of the Ventura Freeway, there is a uniquely designed area meant to emulate a more rural setting called Melody Acres. Tarzana contains two country clubs (with golf courses) in the Santa Monica Mountains: El Caballero Country Club and Braemar Country Club. At the remote southern end of Reseda Blvd., there are a number of gated communities, including Mulholland Park, Silverhawk Ridge, Monte Verde, and Braemar Estates.

North of the Boulevard, where a smaller portion of the population lives, there are fewer houses and more apartment buildings. Tarzana extends north to Victory Boulevard, encompassing a wide swath of medium-density housing.